Colorectal Cancer
Lung Cancer
Breast Cancer
Kidney Cancer
Other Cancers
Tumor cells release a protein called vascular endothelial growth factor (VEGF). VEGF stimulates the growth of new blood vessels, which tumors need to grow and spread.
Avastin binds to VEGF, preventing it from interacting with its receptors on endothelial cells. Endothelial cells are the cells that line blood vessels.
Without VEGF signaling, endothelial cells cannot form new blood vessels. This starves the tumor of oxygen and nutrients, which can slow its growth or even shrink it.
It’s important to understand that Avastin 400mg Injection is administered only by a healthcare professional, never at home. Here’s what you need to know about its administration:
When it comes to receiving Avastin 400mg Injection, it’s essential to know that this treatment is only administered by a healthcare professional in a medical setting. Here’s a simple guide on what to expect:
Intravenous Infusion: Avastin is given through a process called intravenous infusion, where it’s slowly dripped into a vein via a thin tube.
Duration: Typically, the infusion takes about 30-90 minutes to complete.
Frequency: Depending on your specific treatment plan, you might receive the injection every two or three weeks.
Dilution: A healthcare professional will prepare your injection by diluting the Avastin solution with sterile saline.
Aseptic Technique: To avoid contamination, they’ll follow proper aseptic techniques during the preparation.
Comfort and Positioning: You’ll be seated or lying down comfortably in the treatment area.
Insertion of Needle: A small needle will be inserted into a vein, usually in your arm, for the infusion.
Infusion Process: The diluted Avastin solution will then be infused slowly through the tube.
Monitoring: Throughout the infusion, you’ll be closely monitored for any potential reactions or side effects.
Avastin is a medication used to treat various types of cancer, and its dosage varies depending on the specific cancer type. Here’s a simplified guide to the recommended dosages for Avastin in different cancer treatments:
Initial Dosage: 5 mg/kg every 2 weeks, used with intravenous 5-fluorouracil-based chemotherapy.
Adjusted Dosage: If the disease progresses, the dosage may be increased to 10 mg/kg every 2 weeks or 5 mg/kg every week.
Recommended Dosage: 15 mg/kg every 3 weeks, in combination with carboplatin and paclitaxel.
During Radiotherapy: 10 mg/kg every 2 weeks, combined with radiotherapy and temozolomide.
Post-Radiotherapy: Continue with 10 mg/kg every 2 weeks as a single agent.
Ovarian, Fallopian Tube, or Primary Peritoneal Cancer:
Initial Phase: 15 mg/kg every 3 weeks, alongside carboplatin and paclitaxel.
Maintenance Phase: After the initial treatment, continue with 15 mg/kg every 3 weeks as a single agent.
Recommended Dosage: 15 mg/kg every 3 weeks, following the administration of 1,200 mg of atezolizumab. Continue until disease progression or unacceptable toxicity is observed.
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